
Long Acting Injectables
Long acting injectables (LAIs) are medications administered by a healthcare provider that release gradually over several weeks or months. Depending on the medication, they can replace daily doses of that same medicine and make it easier to maintain a consistent treatment routine.
At AMC Psychiatric Services, we offer long acting injectable medications as part of individualized care. Your provider will help determine whether an injectable option fits your diagnosis, medical history, and treatment goals.

How Do Long Acting Injectables Work?
Long acting injectables use an extended-release formulation that allows medication to enter the body gradually after an injection. Instead of taking that medication every day, you receive scheduled injections at intervals determined by the specific product.
Injection schedules vary. Some medications are administered every two weeks, while others are given monthly or less frequently. Your provider will explain your schedule and whether oral medication is needed before or during the transition.

What Are the Benefits of Long Acting Injectables?
For appropriate patients, long acting injectables can simplify medication management and support consistent treatment. Potential benefits include:
- Fewer daily doses to remember: Scheduled injections reduce the need to remember a daily pill for that medication.
- More consistent medication delivery: Gradual release can help reduce fluctuations in medication levels between doses.
- Improved treatment adherence: Regular appointments help patients stay on schedule and give providers an opportunity to monitor progress.
- Reduced risk of symptom relapse: For certain psychiatric conditions, consistent antipsychotic treatment may help reduce the risk of symptoms returning, particularly when missed doses have contributed to relapse.
Benefits vary by medication, condition, and individual response. Injectable treatment still requires regular follow-up and monitoring.
Which Injectable Medications Are Offered at AMC Psychiatric Services?
AMC providers administer injectable medications based on each patient’s clinical needs. Options include:
Risperidone
- Long acting risperidone is an antipsychotic medication used to treat schizophrenia and, with certain formulations, provide maintenance treatment for bipolar I disorder. The injection schedule and need for temporary oral medication depend on the formulation prescribed.
Aripiprazole, Including Abilify Maintena
- Long acting aripiprazole formulations, such as Abilify Maintena, are used to treat schizophrenia and provide maintenance treatment for bipolar I disorder in adults. Your provider will review the appropriate formulation, dosing schedule, and steps needed to begin treatment.
Extended-Release Naltrexone
Extended-release naltrexone, commonly known as Vivitrol, is a monthly injection used to treat alcohol dependence or help prevent relapse to opioid dependence after detoxification. It works differently from antipsychotic injections and is prescribed as part of a comprehensive treatment plan.
Patients must meet specific medical requirements before starting naltrexone, including an appropriate opioid-free period. Your provider will assess readiness before administering treatment.

Who May Benefit From Long Acting Injectable Treatment?
Long acting injectables may be an option for people who prefer fewer medication doses, have difficulty remembering daily medication, or have experienced symptom recurrence related to missed doses.
They may also suit patients who already take medication consistently but prefer scheduled injections. Choosing an injectable is a shared decision between you and your provider.

What Happens at an Injection Appointment?
Your provider reviews your symptoms, medication response, and any side effects before administering the prescribed injection. Appointments also provide an opportunity to discuss changes in your health, ask questions, and plan your next dose.
Before treatment begins, your provider will explain potential risks, required monitoring, and any preparation. Some medications require an oral trial to establish tolerability or temporary oral treatment when injections begin.

